Publications by authors named "S D Sharifi"
Significant wellbeing concerns have been reported nationally among resident doctors. A peer-led survey at University Hospitals Birmingham NHS Foundation Trust revealed high burnout risk and dissatisfaction. The Doctor Wellbeing Group (DWG) was established to address these multifaceted concerns by supporting resident doctors to run quality improvement projects to improve working conditions, with consultant supervision and regular reports to stakeholders.
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- - The study presents a two-phase approach to develop and characterize novel hybrid nano-photosensitizers for targeting breast cancer, integrating molecular simulations with laboratory and animal experiments for improved model accuracy.
- - In the first phase, researchers used artificial intelligence and molecular docking to identify pharmacokinetic weaknesses and synthesized biohybrid nanoplatforms, assessing their stability in vivo.
- - The second phase optimized photodynamic treatment variables and demonstrated that the optimized nano-photosensitizer effectively killed triple-negative cancer cells in both static and dynamic cultures, indicating a promising strategy for enhancing cancer treatment.