Publications by authors named "S D Savaliya"
Background: Empagliflozin (EMPA) is an SGLT2 inhibitor, a new class of anti-diabetic medication, indicated for treating type-2 diabetes. Its low permeability, poor solubility and bioavailability limits its use in management of diabetes. The study was aimed to formulate EMPA loaded polymeric micelles (PMs) to overcome these obstacles in oral absorption.
View Article and Find Full Text PDFStudy of Antimicrobial Resistance (AMR) in spp. in India.
Recent Adv Antiinfect Drug Discov
May 2024
Article Synopsis
- * The article highlights that resistance to antibiotics is complicating treatment for infections, notably those caused by certain bacteria, which are a leading cause of diarrheal deaths.
- * It emphasizes the importance of improved surveillance and the need for new treatment strategies to address the complex issue of AMR, which impacts multiple sectors including health, agriculture, and the environment.
Parkinson's disease (PD) is a neurodegenerative movement disorder that is routinely treated with levodopa. Unfortunately, long-term dopamine replacement therapy using levodopa leads to levodopa-induced dyskinesias (LID), a significant and disabling side-effect. Clinical findings indicate that LID typically only occurs following the progression of PD motor symptoms from the unilateral (Hoehn and Yahr (HY) Stage I) to the bilateral stage (HY Stage II).
View Article and Find Full Text PDFSelf-expanding covered stent placement to treat a pseudoaneurysm caused by iatrogenic vertebral artery injury.
J Cerebrovasc Endovasc Neurosurg
September 2021
Vertebral artery injuries account for approximately 19% of cerebral vascular injuries and are typically managed conservatively. However, some patients require operative intervention to gain control of an active hemorrhage, either via surgical ligation or endovascular intervention. We present a case of iatrogenic vertebral artery injury occurring during cervical spine surgery which was treated emergently with a self-expanding covered stent.
View Article and Find Full Text PDFBackground: The increasing burden of noncommunicable diseases (NCDs) and large proportion of adolescent population in India; crafts the dynamics of NCD risk factors. Most of the NCD risk factors are behaviorally acquired which are due to change in lifestyle during adolescent age groups.
Objective: This study aims to determine the prevalence of risk factors among school-going adolescents in one of district of Gujarat state, India.