Publications by authors named "S D Saroj"

Environmental factors play a crucial role in bacterial virulence. During transmission, in a non-host environment bacteria are exposed to various environmental stress which could alter bacterial physiology and virulence. N.

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Hydroxyapatite (HA) is an important constituent of natural bone. The properties of HA can be enhanced with the help of various ionic substitutions in the crystal lattice of HA. Iron (Fe) is a vital element present in bones and teeth.

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  • * A recent genomic study identified extensively drug-resistant strains of these bacteria from a blood sample of a patient with a specific kidney condition (pauci-immune crescentic glomerulonephritis), utilizing whole-genome sequencing to analyze their characteristics.
  • * The analysis revealed distinct genome sizes and features, including multiple virulence factors and antimicrobial resistance mechanisms, emphasizing the need to understand these polymicrobial infections for better treatment strategies.
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CSF rhinorrhea secondary to anterior skull base defect may be spontaneous or traumatic (accidental or iatrogenic), spontaneous being common in middle aged, obese females. Nowadays endoscopic technique is gold standard for anterior skull base defect repair. The graft materials available may be autologous (fat, temporalis fascia, fascia lata, septal mucosa, cartilage, middle turbinate), homologous e.

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  • - Klebsiella pneumoniae is a serious Gram-negative bacterium known for causing infections and developing antibiotic resistance, especially in its hypervirulent forms that are increasingly affecting community health.
  • - A study analyzed 225 K. pneumoniae isolates over a year at a hospital in Pune, India, finding that 76% formed strong biofilms and many carried genes related to antibiotic resistance and virulence.
  • - The research highlights the urgent need for monitoring and managing these infections due to their potential threats to public health, as strong biofilm formation and multidrug resistance were prevalent in the isolates.
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