Publications by authors named "S D Pack"

Article Synopsis
  • Microalgae are a promising and sustainable biomass resource, but research on large-scale harvesting processes is limited despite available technologies.
  • A new harvesting system has been developed that combines dissolved air flotation and screw-press filtration, resulting in lower energy consumption and high biomass harvest efficiency (93%) for chlorella sp.
  • This system is more energy-efficient than traditional centrifugation methods, using 60.5% less energy, and demonstrates strong potential for scaling up microalgae biomass harvesting for industrial use.
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Aging is closely linked to various health challenges, including cardiovascular disease, metabolic disorders, and neurodegenerative conditions. This study emphasizes the critical role of bioactive compounds derived from marine sources, such as antioxidants, omega-3 fatty acids, vitamins, minerals, and polysaccharides, in addressing oxidative stress, inflammation, and metabolic disorders closely related to aging. Incorporating these materials into functional foods not only provides essential nutrients but also delivers therapeutic effects, thereby promoting healthy aging and mitigating age-related diseases.

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Airborne particulate matter less than 10 µm in diameter (PM10) is recognized as a significant environmental risk factor for hemorrhagic stroke (HS), as evidenced by epidemiological studies that link PM10 with the heightened cerebrovascular mortality related to HS. Nonetheless, the molecular mechanisms underlying this association remain unknown. Cerebral aneurysm (CA), an etiological factor of HS, is characterized by a bulge resulting from the abnormal loss of the muscular layer of a cerebral artery, comprising brain vascular endothelial cell (BVEC) and vascular smooth muscle cell (VSMC).

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Metribuzin, a widely used triazine herbicide, persists in agricultural soils and poses significant environmental pollution threats globally. The aim of this study was to investigate the biodegradation of metribuzin by actinobacterial strains in vitro at different environmental conditions. From an initial screen of 12 actinobacterial strains, four bacteria exhibited robust growth in the presence of the metribuzin as the sole carbon source at 50 mg/L concentration.

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Article Synopsis
  • Indeterminate dendritic cell histiocytosis (IDCH) is a rare condition marked by a buildup of specific histiocytes, with particular immunophenotypic features and clinical presentations, mostly in older adults.
  • The study analyzed 43 cases, showing that many patients had skin or lymph node involvement, and a significant number had related blood cancers or other histiocytic diseases.
  • Genetic analyses identified common mutations (like KRAS and BRAF) and unique gene fusions, helping to clarify IDCH's molecular profile and its potential impact on diagnosis and treatment strategies.
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