Probl Radiac Med Radiobiol
December 2023
The review is devoted to the application of the new perspective class of radionuclide tracers, based on inhibitors of the fibroblast activation protein (FAP), which is a marker of cancer-associated fibroblasts of microenvironment of most malignant tumors. FAP inhibitors (FAPI) can be labeled by a wide spectrum of radionuclides, which can provide both radionuclide diagnostics and radionuclide therapy. It was showed, that the diagnostic efficacy of FAPI positron emission tomography/computed tomography (PET/CT) in various cancers is similar to 18F-fluorodesoxyglu-cose-PET/CT or superior.
View Article and Find Full Text PDFImmediate and late follow—up results of oncoplastic operations, performed in 75 patients, suffering mammary gland cancer (MGC), including in 22—a delayed, and in 53—primary reconstruction of the breast, were analyzed. In 66 patients musculo— cutaneous flaps on nutrient pedicle, taken up from the back and abdominal wall tissues, with underlying mammary gland endoprosthesis,were applied as a transplant. Ductal invasive MGC was diagnosed in 70 patients, invasive lobular one — in 5.
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