Publications by authors named "S D Manjula"
Background: Premenstrual syndrome (PMS) is known to be a prevalent health concern affecting a significant number of women globally and yoga is found to be beneficial in such psychosocial disorders.
Objective: To evaluate the effectiveness of a structured yoga intervention by comparing pre-and post-intervention changes in the severity of PMS symptoms and cardiac autonomic functions in young, healthy female students over the course of three menstrual cycles.
Methods: The present study is a trial conducted in the Department of Physiology, Kasturba Medical College, Manipal which consists of 49 young, healthy female volunteers suffering from moderate PMS.
The aim of the present pilot study is to design, validate, and check the feasibility and efficacy of the designed meditation module on etiological and preventive factors in primary hypertensive patients (PHP). The systematic and detailed meditation module was formulated to prevent the complications of hypertension. The designed module was validated by 5 subject experts in the field of complementary and alternative therapy and research.
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- Cyclophosphamide (CYL) is a commonly used cancer chemotherapy drug that can lead to severe memory impairment due to its toxic effects from free radical generation.
- A study explored the protective effects of noni fruit juice (NJ), known for its antioxidant properties, against memory issues caused by CYL in Swiss albino mice.
- Results showed that while CYL treatment caused short-term memory impairment, combining NJ with CYL significantly improved memory and biochemical markers associated with oxidative stress and neuroprotection in the mice.
Purpose: To compare the efficacy, safety, and tolerability of lifitegrast 5% versus carboxymethylcellulose (CMC) 0.5% in adult patients with dry eye disease (DED).
Methods: A total of 370 eligible patients with DED were randomized equally to receive twice-daily doses of a single drop in each eye of either lifitegrast 5% or CMC 0.
Aim: The present study compared the safety, efficacy, and tolerability of the new fixed-dose combination (FDC) of telmisartan 40 mg + bisoprolol 5 mg (TBP) tablets with the existing comparator FDC telmisartan 40 mg + metoprolol succinate ER 50 mg (TMS) tablets in patients with stage 1 and stage 2 hypertension.
Methodology: The multicentric, double-blind, parallel-group, comparative, prospective, phase-III clinical study involved 264 subjects with stage 1 and stage 2 hypertension from 10 centres across India. The selected subjects were randomized into two groups: group A received the TMS and group B received the new FDC TBP.