Roadmap for the Development and Implementation of Entrustable Professional Activities to Enable Effective Clinical Training.

In the field of clinical training, entrustable professional activities (EPAs) generally deal with those activities that health-care professionals will be encountering in their routine practice, and thus exposure to these activities prepares them for their future clinical practice. Workplace-based assessment tools have been used to assess the progress of medical students across these defined EPAs. The act of development of EPAs essentially requires the adoption of a systematic process to identify and define the core tasks and responsibilities that medical students must be able to perform independently in a specific specialty.

Palliative endoscopic treatment of malignant central airway obstruction.

Purpose: To examine the outcome of palliative endoscopic treatment of malignant central airway obstruction (CAO) and identify predictors for Days Alive and Out of Hospital (DAOH), overall survival and treatment related complications.

Methods: Consecutive adult patients treated endoscopically for malignant CAO at Aarhus University Hospital from 2012 to 2022 were included in the study. Statistical analyses were carried out to identify predictors for DAOH, survival and complications.

Design and characterization of hollow microneedles for localized intrascleral drug delivery of ocular formulations.

Effective drug delivery to the posterior segment of the eye remains a challenge owing to the limitations of conventional methods such as intravitreal injections, which are associated with significant side effects. This study explored the use of hollow microneedles (HMNs) for localized intrascleral drug delivery as a minimally invasive alternative. Stainless steel HMNs with bevel angles of 30°, 45°, 60°, and 75° were fabricated using wire electron discharge machining.

Exploring the impacts of climate change and identifying potential adaptation strategies for sustainable rice production in Thailand's Lower Chao Phraya Basin through crop simulation modeling.

The lower Chao Phraya River Basin (CPRB) in Thailand, a major rice-producing area, is grappling with increased water scarcity alongside more frequent floods and droughts, necessitating effective adaptation strategies to sustain agricultural productivity. This study assesses the impacts of climate change on rice yield and irrigation water use, using the DSSAT-CERES-Rice model. Based on these findings, potential genotype- and management-based adaptation strategies were recommended.

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Preoperative virtual surgical planning and the use of 3D-printed patient-specific models and cutting guides are increasingly being used in the reconstruction of mandibular defects with a free bone flap. This technology offers several advantages over conventional surgery, such as reduced operating time, reduced bone flap ischaemia time, and the ability to perform more complex and precise reconstructions. This review presents the evidence supporting 3D-assisted surgery for mandibular defect reconstruction and discusses the utilisation of commercial vendors versus in-house 3D-printing solutions.