Lophine incorporated azo dye as a novel colorimetric sensor for multiple metal ions.

A single molecule sensor for several analytes is indeed desired by the scientists around the world due to obvious advantages. In this report we present a new class of Lophine incorporated azo dyes that has capacity of differential colorimetric detection of several metal ions. Interestingly the sensor was found to have pH dependent selective response towards several metals.

Cardiac Magnetic Resonance Imaging in Lyme Carditis-A Case Series and Review of Literature.

Lyme carditis is an uncommon but potentially fatal manifestation of early disseminated Lyme disease. Timely diagnosis poses a clinical challenge due to the highly variable and non-specific symptomatology that can be easily overlooked, as well as the limited availability of specific and non-invasive diagnostic tests for assessing cardiac involvement. While cardiac magnetic resonance (CMR) imaging is the standard imaging modality for diagnosing various etiologies of cardiomyopathy, its application in Lyme carditis remains understudied.

Genetics, manifestations, and management of catecholaminergic polymorphic ventricular tachycardia.

Purpose Of Review: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a devastating heritable channelopathy that can lead to sudden cardiac death in children and young adults. This review aims to explore genetics, the cardiac and extracardiac manifestations of mutations associated with CPVT, and the challenges involved with managing phenotypically variable variants.

Recent Findings: The understanding of the genetics and mechanisms of CPVT continues to grow with recent discoveries including alternative splicing of cardiac TRDN and calmodulin gene variants.

Perceptions of patients and stakeholders on a prenatal sickle cell disease screening and its results among tribal populations of Gujarat: a participatory mixed-method research.

Prenatal screening (PNS) for Sickle Cell Disease (SCD) offers a potential avenue for informed reproductive choices and the sickle elimination initiative of the Government of India. The objective of the study was to explore perceptions and ethical dilemmas surrounding prenatal screening for sickle cell disease and subsequent termination of pregnancy among pregnant women and key stakeholders from the tribal region of Gujarat. The study employed sequential mixed-methods research, embedding a participatory research approach.