Publications by authors named "S D Brass"
Article Synopsis
- The report investigates the safety and effectiveness of 3D-printed aortic models in aortic surgery, especially regarding their sterilization and modification for creating personalized endoprostheses.
- Five identical models were made using patient data, with two sterilized, two disinfected, and one untreated to evaluate any changes from these processes.
- The findings showed no significant structural alterations in the models post-treatment, and both sterilized and disinfected models were free of pathogens, supporting their potential clinical use.
Article Synopsis
- - The study compared outcomes of thoracic endovascular aortic repair (TEVAR) procedures between two settings: standard operating rooms (SOR) and hybrid operating rooms (HOR) at a hospital in Germany, analyzing data from 93 patients over seven years.
- - Results showed that patients in the SOR had significantly lower radiation exposure and fluoroscopy times, but required higher volumes of contrast agent compared to those in the HOR.
- - The findings suggest that while the HOR leads to increased radiation and longer procedure times, it may be preferable for certain patients due to its lower volume of contrast use, especially in older patients with conditions like chronic kidney disease (CKD).
Nicotine Potentially Alters Endothelial Inflammation and Cell Adhesion via .
J Cardiovasc Dev Dis
December 2023
Background: The endothelial cell layer is essential for the maintenance of various blood vessel functions. Major risk factors for endothelial dysfunction that contribute to aortic pathologies such as abdominal aortic aneurysm (AAA) and aortic dissection (AD) include smoking tobacco cigarettes and hypertension. This study explores the effects of nicotine (Nic) and angiotensin II (Ang II) on human aortic endothelial cells (HAoECs) at a transcriptional level.
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- Acute aortic dissection (AAD) is a serious health issue that can happen if the inner lining of a large blood vessel tears, and factors like high blood pressure and smoking make it more likely.
- Researchers studied how nicotine, a chemical in cigarettes, angiotensin II (a substance that can raise blood pressure), and alcohol affect heart cells by testing these substances in different amounts and observing changes in cell behavior.
- They found that alcohol and angiotensin II made cells less healthy and changed how well they stuck together and moved, suggesting that these substances might make it easier for an important blood vessel to get damaged.
Severe Monkeypox in Hospitalized Patients - United States, August 10-October 10, 2022.
MMWR Morb Mortal Wkly Rep
November 2022
Article Synopsis
- * A CDC report analyzed 57 hospitalized monkeypox patients from August to October 2022, revealing that 82% had HIV, most were male (95%), and 68% were non-Hispanic Black; 30% needed ICU care, and 21% died due to severe symptoms.
- * Health care providers are advised to test sexually active monkeypox patients for HIV and consider aggressive treatment for those who are severely immunocompromised