World J Otorhinolaryngol Head Neck Surg
December 2024
Objective: Our study aimed to investigate the ototoxicity associated with the iron chelator deferasirox in patients with β-thalassemia major, who were receiving regular transfusion therapy, along with evaluating the data on audiological tests using appropriate statistical tests.
Methods: A cross-sectional observational study was conducted on 100 transfusion-dependent β-thalassemia major patients on oral iron chelating agent-deferasirox. Pure tone audiometry (PTA) and distortion product otoacoustic emissions (DPOAE) was carried out in all patients to assess the auditory side effects of the drug.
Indian J Otolaryngol Head Neck Surg
December 2024
Indian J Otolaryngol Head Neck Surg
December 2024
To study the prevalence and determinants of Noise Induced Hearing Loss (NIHL) among industrial workers. To access the benefit of Distortion Product Oto Acoustic Emissions (DPOAEs) in its early detection as compared to Pure Tone Audiometry (PTA). Detailed in-person questionnaires were filled followed by general and otological examination viz.
View Article and Find Full Text PDFIndian J Otolaryngol Head Neck Surg
December 2024
Introduction: Cardiomyopathy is a complex condition influenced by multiple genes and environmental factors. It has been suspected that cardiomyopathy is affected by the ACE gene's I/D polymorphism. Our study aimed to evaluate the association between this polymorphism and cardiomyopathy risk in the Jammu population of North India, alongside a meta-analysis to determine the specific risks associated with different types of cardiomyopathy.
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