Abstract concepts and expertise: the case of institutional concepts.

Recent views recognize that abstract concepts encompass a variety of exemplars, each relying on different dimensions, including not only sensorimotor but also inner, linguistic, and social experiences. How these dimensions characterize types of abstract concepts, and whether their weight varies across contexts and individuals remains an open question. We investigated the role of linguistic and social situations in the processing of institutional concepts, such as justice, by individuals with different levels of expertise.

Injection site reactions after dupilumab or tralokinumab for atopic dermatitis.

Injection site reaction (ISR) is a local phenomenon defined as a constellation of symptoms, including swelling, erythema, pruritus, and pain around the site of injection. ISR is reported as a frequent adverse event after subcutaneous injection (SCI) of several biologics. We performed an observational real-life study to compare dupilumab and tralokinumab as regards ISR, analysing frequency, duration and intensity of symptoms related to SCI.

Delayed ocular disengagement from arousing scenes.

Visual exploration of the world is supported by eye movements which can be speeded up or delayed depending on bottom-up stimulation, top-down goals, and prior associations. Previous studies observed faster initiation of saccades toward emotional than neutral natural scenes; however, less is known concerning saccades which originate from emotional, compared with neutral, scenes. Here, we addressed this issue by examining a task in which participants continuously moved their gaze from and toward pictures (natural scenes), which could be emotional or neutral, and changed position in every trial.

Metastatic Dissemination: Role of Tumor-Derived Extracellular Vesicles and Their Use as Clinical Biomarkers.

Cancer is a major cause of mortality in humans; often, rather than the primary tumor, it is the presence of metastases that are the cause of death. Extracellular vesicles (EVs) are small structures released by both normal and cancer cells; regarding the latter, they have been demonstrated to modulate almost all cancer-related processes, such as invasion, angiogenesis induction, drug resistance, and immune evasion. In the last years, it has become clear how EVs are widely involved in metastatic dissemination as well as in pre-metastatic niche (PMN) formation.

Novelty and learning in cognitive control: evidence from the Simon task.

While information that is associated with inappropriate responses can interfere with an ongoing task and be detrimental to performance, cognitive control mechanisms and specific contextual conditions can alleviate interference from unwanted information. In the spatial correspondence (Simon) task, interference has been consistently shown to be reduced by spatial non-correspondence in the previous trial (i.e.