Publications by authors named "S Cuzzocrea"

Background: Several epidemiological studies and intervention trials have demonstrated that grapes and blueberries, which are rich in flavanols, can lower the risk of cardiovascular disease. However, the mechanisms of action of these compounds remain unclear due to their low bioavailability.

Objective: This study aimed to characterize the sensory properties, blood flow velocity, and oxidative stress of a polyphenol rich grape and blueberry extract (PEGB) containing approximately 16% flavanols (11% monomers and 4% dimers).

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Insect protein hydrolysates (PH) are emerging as valuable compounds with biological activity. The aim of the present study was to assess the potential cytoprotective effects of PH from the Black Soldier Fly (BPH, in the range 0.1-0.

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Article Synopsis
  • - Metabolic syndrome (MetS) is a growing public health issue linked to changes in eye health, particularly leading to conditions like diabetic retinopathy, influenced by factors such as osteopontin (OPN).
  • - In a study that induced MetS in animals through a 30% fructose diet over three months, researchers tracked changes in weight, food intake, and biochemical parameters, revealing significant weight gain and alterations akin to MetS in humans.
  • - Findings showed a time-dependent increase in OPN and microglia levels, alongside a decline in proteins important for cell junctions, suggesting that monitoring OPN could serve as an early indicator of retinal damage in MetS patients, potentially aiding in the prevention of serious complications
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