Increased dehydroepiandrosterone (DHEA) is associated with anxiety in adolescent girls.

The pubertal period is a time of rapid increase in the incidence of anxiety disorders, and thus, pubertal hormones may play a role in the precipitation of anxious psychopathology. DHEA, a steroid hormone that surges in adolescence, has been previously linked to anxiety, although the direction of this effect has been mixed. Using a cross-sectional design in a sample of 286 adolescent girls, the present study examined associations between salivary DHEA concentrations and self-report and interview-based measures of anxiety while controlling for pubertal status, menarche status, assessment time of day, and other hormones including testosterone, estradiol, and progesterone.

The development of the error-related negativity in large sample of adolescent females: Associations with anxiety symptoms.

Anxiety is the most common form of psychopathology and tends to begin early in the course of development. Given this, there is great interest in identifying developmental changes in neural systems that may delineate healthy versus anxious trajectories. A substantial amount of work has focused on the error-related negativity as a neural marker of anxiety.

Real-time support of pediatric diabetes self-care by a transport team.

OBJECTIVE The study seeks to improve access for underserved patients via novel integration of Pedi-Flite (a critical care transport team) and to validate whether this safely enhances diabetes care and effectively expands the endocrine workforce. RESEARCH DESIGN AND METHODS The study retrospectively analyzed pager service use in a cohort of established diabetic patients (n = 979) after inception of Pedi-Flite support. Outcomes included incidence and severity of recurrent diabetic ketoacidosis (DKA) and cost savings generated from reduced referrals to the emergency department (ED) and on-call endocrinologist.

Sleep-stage scoring in the rat using a support vector machine.

Analysis and classification of sleep stages is a fundamental part of basic sleep research. Rat sleep stages are scored based on electrocorticographic (ECoG) signals recorded from electrodes implanted epidurally and electromyographic (EMG) signals from the temporalis or nuchal muscle. An automated sleep scoring system was developed using a support vector machine (SVM) to discriminate among waking, nonrapid eye movement sleep, and paradoxical sleep.