Publications by authors named "S Collaud"
Objective: Ewing sarcoma (EWS) of the mediastinum is extremely rare, with only a few cases reported in the literature. We aimed to gain a better understanding of primary mediastinal EWS, describing patients treated within two international, multicenter, prospective, randomized EWS trials.
Methods: Data from patients with primary mediastinal EWS were retrieved from the database of the EURO-E.
Background: Whole lung transpulmonary chemoembolization using a combination of doxorubicin (DXO) and degradable starch microspheres (DSM-TPCE) might be a promising treatment option in soft tissue sarcoma. To pave the way for clinical studies, this study aimed to evaluate the short-term effects of DSM-TPCE with DXO using an ex vivo isolated lung perfusion (ILP) model.
Methods: Nine lung specimens retrieved from patients undergoing lobectomy underwent ex vivo ILP.
Prognostic factors in clear cell sarcoma: an analysis of soft tissue sarcoma in 43 cases.
J Cancer Res Clin Oncol
November 2024
Article Synopsis
- Clear cell sarcoma (CCS) and its similar tumor, malignant gastrointestinal neuroectodermal tumor/sarcoma (GINET), often lead to local and distant relapses, with limited success from systemic treatments.
- A study analyzed data from 43 patients, revealing a 5-year overall survival rate of 42%, with most tumors being EWSR1::ATF1-translocation-positive and showing a high rate of metastasis.
- The findings highlighted that complete tumor resection significantly improves survival rates compared to incomplete resection, while systemic treatments and radiation were largely ineffective.
Bilateral lung volume reduction surgery outperforms the unilateral approach in functional improvement.
Interdiscip Cardiovasc Thorac Surg
October 2024
Objectives: Lung volume reduction surgery (LVRS) is an established treatment approach for patients with severe pulmonary emphysema, enhancing lung function and quality of life in selected patients. Functional benefits and outcomes after uni- versus bilateral lung volume reduction remain a topic of debate.
Methods: A retrospective analysis of patients undergoing LVRS from January 2018 to October 2022 was conducted.
Background: The association of physical activity (PA) and lung function (LF) varies from no measurable effect to delayed LF decline. We assessed the association between accelerometery-assessed PA and LF in a sample of apparently healthy, community-dwelling subjects.
Methods: We included two cross-sectional studies using data from the PneumoLaus study (2014-17 and 2018-21), conducted in Lausanne, Switzerland.