A Deep Dive into the Complex Chemical Mixture and Toxicity of Tire Wear Particle Leachate in Fathead Minnow.

The ecological impact of tire wear particles in aquatic ecosystems is a growing environmental concern. We combined toxicity testing, using fathead minnow (Pimephales promelas) embryos, with nontarget high-resolution liquid chromatography Orbitrap mass spectrometry to characterize the toxicity and chemical mixture of organic chemicals associated with tire particle leachates. We assessed: 1) exposure to tire particle leachates after leaching for 1-, 3-, and 10-d; and 2) the effect of the presence and absence of small tire particulates in the leachates.

Chronic Embryo-Larval Exposure of Fathead Minnows to the Pharmaceutical Drug Metformin: Survival, Growth, and Microbiome Responses.

Metformin is a glucose-lowering drug commonly found in municipal wastewater effluents (MWWEs). The present study investigated the chronic effects of metformin in early-life stages of the fathead minnow (Pimephales promelas). Endpoints assessed were growth, survival, and deformities.

Increased Temperature and Turbulence Alter the Effects of Leachates from Tire Particles on Fathead Minnow ().

Tire particles are of concern as a stressor due to the combination of their chemical constituents, high emission rates, and global distribution. Once in the environment, they will interact with physical parameters (e.g.

The effect of red wine on colour stability of three different types of esthetic restorative materials: An study.

Aim And Objective: To evaluate the effect of red wine on color stability of three different esthetic restorative materials such as nanohybrid composites, conventional restorative glass ionomer cement (GIC), and feldspathic porcelain.

Materials And Methods: The color stability of test materials was determined using a spectrophotometer. A total of 30 specimens were prepared (10 from each) from each material on a round metal mold (11 mm diameter and 2 mm deep).

Altered expression of metabolites and proteins in wild and caged fish exposed to wastewater effluents in situ.

Population growth has led to increased global discharges of wastewater. Contaminants that are not fully removed during wastewater treatment, such as pharmaceuticals and personal care products (PPCPs), may negatively affect aquatic ecosystems. PPCPs can bioaccumulate causing adverse health effects and behavioural changes in exposed fish.