Publications by authors named "S Cingelova"
Article Synopsis
- In acute promyelocytic leukemia (APL), combining all-trans retinoic acid (ATRA) and arsenic trioxide (ATO) shows a unique effect on differentiation syndrome (DS), making it different from the previously recognized ATRA syndrome due to its specific symptoms and patterns.
- A study from 2013-2022 categorized APL patients into three treatment groups and analyzed the occurrence of leukocytosis and DS within the first 25 days, finding a 43.8% incidence of DS and elevated liver enzymes in the ATRA/ATO standard-risk group.
- The results suggest that liver changes may be linked to the treatment's effects on leukocyte differentiation and call for a reevaluation of the DS definition and
Introduction: In patients with acute myeloid leukemia (AML), allogeneic hematopoietic stem cell transplantation (HSCT) remains the priority treatment option as the most effective prevention of relapse. When an HLA-matched sibling is available, these transplants are preferred.
Objectives: We stratificated patients according to risk, disease state (an active disease, the 1st or 2nd complete remission ‒ CR1, CR2, which was achieved after the 1st or 2nd induction) and type of graft (from brother or sister).
Introduction: The results of treatment of acute lymphoblastic leukemia (ALL) from the low population countries are missing in the literature.
Patients And Methods: We retrospectively examined biological characteristics and survival of 90 patients with ALL.
Results: At median follow-up 17 months, 52 men and 38 women were eligible for the analysis with median age 43 years (18-74).
Oxidative stress plays a significant role in development and progression of cancer, including urothelial carcinomas. TBARS (Thiobarbituric acid reactive substances) represents a marker of oxidative stress increased in various diseases. In this prospective study, we tested the hypothesis of plasma TBARS concentration and correlation with survival in chemotherapy naïve MUC (metastatic urothelial carcinoma) patients.
View Article and Find Full Text PDFMyeloid sarcoma is a rare presentation of acute leukemia as a solid tumor at various extramedullary sites. It may present concurrently, before or after the onset of systemic bone marrow leukemia. Unusual clinical localization may lead to misdiagnosis, or delayed diagnosis and treatment.
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