Publications by authors named "S Choyke"
Article Synopsis
- PFAS are harmful chemicals that pose risks to human health and the environment, notably through fish consumption, which is a significant exposure source.
- The research highlights inconsistencies in regulations between the EU and USA regarding PFAS levels in fish, focusing on various regions and types of fish.
- While most fish samples had PFAS levels below EU pollution standards, they could still exceed safe intake limits when consumed, complicating health risk messaging.
Article Synopsis
- A study examines how to identify bioactive per- and polyfluoroalkyl substances (PFAS) in environmental samples, as only a few of these compounds are regularly monitored.
- It combines toxicity testing, targeted chemical analyses, and suspect screening to find unknown substances in PFAS-contaminated sediments, particularly looking at their interaction with the thyroid hormone distributor protein, transthyretin (TTR).
- The researchers determined that certain PFAS, like PFHpS and PFOS, have varying potencies for TTR binding, but not all observed bioactivity in sediment samples was linked to the known PFAS, leading to the identification of five additional candidates through suspect screening.
Historical releases of aqueous film forming foam (AFFF) are significant sources of poly- and perfluoroalkyl substances (PFASs), including perfluoroalkyl acids (PFAAs) and their precursors, to the environment. While several studies have focused on microbial biotransformation of polyfluorinated precursors to PFAAs, the role of abiotic transformations at AFFF-impacted sites is less clear. Herein, we use photochemically generated hydroxyl radical to demonstrate that environmentally relevant concentrations of hydroxyl radical (OH) can play a significant role in these transformations.
View Article and Find Full Text PDFPerfluorooctane sulfonate (PFOS) is among the most commonly per- and poly-fluoroalkyl substances (PFAS) found in environmental samples. Nevertheless, the effect of this legacy persistent organic contaminant has never been investigated on corals to date. Corals are the keystone organisms of coral reef ecosystems and sensitive to rising ocean temperatures, but it is not understood how the combination of elevated temperature and PFOS exposure will affect them.
View Article and Find Full Text PDFPer- and polyfluoroalkyl substances (PFAS) are compounds manufactured for use in paints, cleaning agents, fire suppressants, nonstick cookware, food containers, and water-resistant products. Concerns about PFAS stem from their ubiquitous presence in the environment, persistence, and variable/uncertain bioaccumulation and toxicity. In the present study, 5 perfluoroalkyl acids and one polyfluoroalkyl substance were administered to white-footed mice (Peromyscus leucopus) to elucidate the kinetics of each chemical over 28 d of exposure.
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