Underuse of Rapid Sequence Intubation Outside the Emergency Department: Insights from Emergency Physicians‒a Preliminary, Retrospective Observational Study.

Objective: Rapid sequence intubation (RSI) involves the administration of induction agents and neuromuscular blockers before endotracheal intubation (ETI). However, RSI seems to be underutilized outside emergency departments (ED). We compared RSI adoption rates and ETI outcomes outside and within EDs and investigated whether RSI adoption affected ETI outcomes outside EDs.

A randomized trial for combination nicotine replacement therapy for smoking cessation among people with HIV in a low-resourced setting.

Objective: The purpose of this study was to evaluate the efficacy of combination nicotine replacement therapy (c-NRT) for smoking cessation among people with HIV (PWH) in South Africa.

Design: We conducted an open label, individually randomized clinical trial.

Methods: Using a two-armed approach, PWH who smoke were randomized to receive either 1) intensive anti-smoking behavioral counseling (BC) or 2) intensive anti-smoking BC plus c-NRT (nicotine patches augmented by nicotine gum).

Measuring and quantifying the effects of pyloric dilatation in patients with delayed emptying of the gastric conduit after Ivor-Lewis esophagectomy using EndoFlip™.

The most common functional challenge after Ivor-Lewis esophagectomy is delayed emptying of the gastric conduit. One of the primary endoscopic treatment strategies is performing a pyloric dilatation. However, the effects of dilation have never been scientifically proven.

Spleen stiffness measurements during recompensation in patients with acutely decompensated liver cirrhosis: preliminary findings of a pilot study.

Background: Acute decompensation (AD) in patients with liver cirrhosis is associated with a dramatic deterioration in prognosis. Immediate initiation of appropriate recompensation measures is essential to improve patient's outcome, although objective parameters for evaluating the success of recompensation are still lacking. Spleen stiffness measurements (SSM) have emerged as promising non-invasive tool to assess clinically significant portal hypertension (CSPH), which is the main driver of acute decompensation.

Influences of serving temperatures on human perceived spiciness intensity of commercial spicy sauces.

The objective of this study was to examine the effects of serving temperatures on the perceived spiciness intensities of commercial spicy sauces, which vary in capsaicinoid content. A total of 9 types of commercially available spicy sauces were used and capsaicinoid content was analyzed using liquid chromatography-mass spectrometry. To assess spiciness intensity, a highly trained panel (n = 6) rated the spiciness intensities at 4, 25, and 60°C.