Publications by authors named "S Chhabra"
Abrocitinib: A Comprehensive Review of its Efficacy and Safety in Dermatology.
Indian Dermatol Online J
October 2024
Article Synopsis
- Abrocitinib is a new oral medication that specifically inhibits JAK-1, targeting inflammation pathways.
- It is currently approved for moderate-to-severe atopic dermatitis and shows potential for treating other inflammatory skin conditions.
- Clinical trials have confirmed its effectiveness and safety, but its future use will depend on practicality within the Indian healthcare context.
Article Synopsis
- The study investigated the effectiveness of measuring collapsibility index (CI) of the subclavian vein (SCV) versus the inferior vena cava (IVC) in predicting hypotension after general anesthesia induction in 132 adult patients.
- During quiet breathing, the SCV-CI and IVC-CI had similar sensitivities and specificities, with SCV-CI showing a sensitivity of 68% and IVC-CI showing 70% for predicting postinduction hypotension.
- The findings suggest both measurement methods are moderately accurate, with a significant positive correlation between SCV-CI and IVC-CI, especially during quiet breathing.
Article Synopsis
- The study investigates the effects of adding dexmedetomidine as premedication to ketofol for sedation in children undergoing MRI, aiming to improve sedation quality and reduce movement artifacts during scans.
- A total of 132 children aged 6 months to 10 years were divided into two groups: one receiving dexmedetomidine and ketofol (DK group) and the other receiving only ketofol (K group). Results showed that the DK group had significantly better sedation quality and scan quality, along with lower propofol dosage.
- The conclusion indicates that administering dexmedetomidine prior to induction enhances sedation quality, reduces the need for additional propofol, and maintains
Objective: To investigate whether induction/augmentation of labor in pregnant women with anemia increases the risk of postpartum hemorrhage (PPH) and whether this risk varied by indications for labor induction/augmentation and by anemia severity in pregnancy.
Methods: In a prospective cohort study of 9420 pregnant women from 13 hospitals across India, we measured hemoglobin concentrations at recruitment (≥28 weeks of gestation) and blood loss after childbirth during follow-up and collected clinical information about PPH. Clinical obstetric and childbirth information at both visits were extracted from medical records.