Publications by authors named "S Cheraghi"
Purpose: We aimed to build a machine learning-based model to predict radiation-induced optic neuropathy in patients who had treated head and neck cancers with radiotherapy.
Materials And Methods: To measure radiation-induced optic neuropathy, the visual evoked potential values were obtained in both case and control groups and compared. Radiomics features were extracted from the area segmented which included the right and left optic nerves and chiasm.
Background: Papillary thyroid carcinoma is the most frequent type of thyroid cancer. The BRAF mutation is associated with tumor progression. We explored the utility of the BRAF molecular testing on fine needle aspiration fixed specimens of patients with confirmed diagnoses of papillary thyroid carcinoma.
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- The BRAF V600E mutation plays a significant role in the progression of anaplastic thyroid cancer (ATC) and serves as an important prognostic biomarker.
- A comprehensive analysis of 34 studies revealed that the BRAF V600E mutation occurred in 33% of 978 ATC patients, highlighting its prevalence.
- The immunohistochemistry (IHC) method for detecting the BRAF V600E mutation showed a sensitivity of 78.9% and specificity of 69.7%, making it a useful diagnostic tool in clinical settings for targeted therapies.
Background: Radiotherapy, a highly effective method of radiation-based treating cancers, can reduce the size of tumors and affect healthy tissues. Radiation-induced lymphopenia as a side effect of radiation therapy can reduce the effectiveness of the treatment.
Objective: This study aimed to examine how taurine can protect peripheral blood lymphocytes from radiation-based apoptosis.
Background: High-dose radiation altering the genetic material in patients' bone marrow cells can lead to hematopoietic radiation syndrome. Accordingly, the presence of radiation protections agents is critical to preventing these adverse effects.
Objective: This study aimed to evaluate the radioprotection of the exclusive or combination effect of resveratrol and crocin extracts at various concentrations on irradiated human lymphocytes.