Immunogenicity and reactogenicity following MMR vaccination in 5-7-month-old infants: a double-blind placebo-controlled randomized clinical trial in 6540 Danish infants.

Background: Measles is a highly contagious viral disease. Vaccinated mothers transfer fewer antibodies during pregnancy, resulting in shortened infant immunity. Earlier primary vaccination might avert the gap in protection.

Case Report: Longitudinal Extensive Transverse Myelitis With Novel Autoantibodies Following Two Rounds of Pembrolizumab.

A 63-year-old male with metastatic non-small cell lung cancer developed longitudinal extensive transverse myelitis (LETM) following two cycles of Pembrolizumab, an immune checkpoint inhibitor (ICI) targeting the programmed cell death receptor 1 (PD-1). Magnetic resonance imaging (MRI) showed centromedullary contrast enhancement at several levels, cerebrospinal fluid (CSF) cytology showed lymphocytic pleocytosis, and indirect immunofluorescence assay (IFA) on the primate cerebellum, pancreas, and intestine revealed strong binding of neuronal autoantibodies to unknown antigens. CSF C-X-C motif ligand 13 (CXCL13) was elevated.

Histopathologic parameters in the evaluation of T1 squamous cell carcinomas of the oral cavity.

Background: Prognostic indicators that could assist in a more precise selection of patients with small oral carcinomas for differentiated therapy would be valuable. A significant fraction of patients with stage I disease have a relatively poor prognosis despite the small size of the tumor, but in general stage I tumors of the oral cavity have a favorable prognosis.

Methods: Seventy-eight patients with stage I (T1N0M0) oral squamous cell carcinoma from two different ENT departments were included in the study.

[Surgical treatment of preauricular fistula. A follow-up study].

Introduction: Our aim was to evaluate the results of surgery on preauricular fistulas over a ten-year period and to determine the postoperative recurrence rate and the factors responsible.

Materials And Methods: Forty-three patients with 51 preauricular fistulas, who had been operated on in the period, 1 August 1990 to 1 August 2000, at the Department of Otolaryngology, Aarhus University Hospital, were asked to participate in a follow-up examination. Thirty-three patients turned up for examination, four patients were interviewed over the telephone, and for the rest the data available from the medical records were used.

[The relevance of mirror examination in modern otorhinolaryngology].

Introduction: The aim of this study was to investigate whether the teaching of mirror examination of the larynx and rhinopharynx is still relevant and to estimate whether it is still a reliable examination.

Material And Method: Twenty-five patients underwent a mirror examination of the larynx and rhinopharynx by a young doctor, a young otorhinolaryngologist, and a senior otorhinolaryngologist.

Results: Not surprisingly the senior otorhinolaryngologist conducted the most adequate examinations.