Surgical palliation combined with synchronous therapy in pancreatic carcinoma.

Palliative surgery has a role in nonresectable pancreatic carcinoma. We attempted to evaluate the efficacy of palliative surgery followed by synchronous therapy in such cases. A group of 92 patients was studied.

Nail-bed melanoma.

In our series of 348 patients treated over a 10-year period, six (1.7%) had their primary lesions in the nail bed. Five of the subungual melanomas occurred in the toes and one in the thumb.

Exposure to radioiodine in the preconception and conception periods. A case report.

A case of radiation exposure shortly before conception is presented. The patient refused abortion and was delivered of a healthy infant. On reconsideration of the case, it was decided that the recommendation to terminate the pregnancy on the grounds of excessive exposure to radiation was unjustified.

Steroid receptors in human renal carcinoma.

Glucocorticoid- and androgen-binding receptors were demonstrated in cytosol of human renal cell carcinomas by the dextran-coated charcoal technique. Sedimentation studies using preparative ultracentrifugation indicated a 7 to 8 S binding component. None of the renal carcinoma cells tested contained detectable estrogen receptors and a few samples had a very low but demonstrable progestin receptor level.