Publications by authors named "S Chabaud"
Over the last decades, the human species has seen an increase in the incidence of pathologies linked to the genitourinary tract. Observations in animals have allowed us to link these increases, at least in part, to changes in the environment and, in particular, to an increasing presence of endocrine disruptors. These can be physical agents, such as light or heat; natural products, such as phytoestrogens; or chemicals produced by humans.
View Article and Find Full Text PDFObjective: Despite significant advances in cancer treatment with targeted therapies and immunotherapies, cytotoxic chemotherapies are still extensively used. Potential cytotoxic contamination in preparing and administrating cytotoxics is still a major source of concern. Besides advanced protections including biological safety cabinets, work surface contamination needs to be continuously controlled to ensure that handling procedures and cleaning were appropriate.
View Article and Find Full Text PDFArticle Synopsis
- Uropathogenic bacteria are the primary cause of urinary tract infections (UTIs), which affect over 50% of women and can recur in up to 30% of patients, causing increased social and economic burdens.
- Current treatments for recurrent UTIs are ineffective, prompting the need for better research models.
- A new human-derived 3D bladder mucosa model was developed using tissue engineering, allowing researchers to study the stages of UTIs, including bacterial adhesion and re-emergence, using specific strains of bacteria for infection.