CD39 expression on immune cells predicts methotrexate response in rheumatoid arthritis patients.

Background/aim: Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting mostly small joints, such as hand and foot joints symmetrically with irreversible joint destruction. In this study, the relationship between CD39 expression and the treatment response of RA patients was examined to investigate its potential as a biomarker that demonstrates treatment response.

Materials And Methods: This study included 77 RA patients and 40 healthy controls (HC).

Congenital Toxoplasmosis and Long-term Outcomes.

Objective: Congenital toxoplasmosis (CT) can have severe early and late sequelae in children. In this study, we aimed to evaluate the demographic, clinical, treatment characteristics of patients diagnosed with congenital infection and to highlight the long-term complications of the patients.

Methods: Patients with CT were included in this study who were followed between 2010 and 2022 in Cukurova University Medical Faculty Hospital.

A single-center study on the biochemical effect and clinical effectiveness of liraglutide in Turkish patients.

Objective: The approval of liraglutide as a treatment option for obesity is a significant development in addressing the major health concerns of diabetes and obesity in recent years. Considering the duration of liraglutide use, pancreatic and hepatic enzymes, weight loss, homeostatic model assessment of insulin resistance (HOMA-IR), discontinuation rationales, and adverse events were studied.

Patients And Methods: From September 2019 to October 2022, 201 participants (125 females and 76 males) aged 18 to 75 were recruited from a single medical facility.

Evaluation of the Possible Contribution of Various Regulatory Genes to Determination of Carpel Number as a Potential Mechanism for Optimal Agricultural Yield.

Various regulatory genes encoding transcription factors and miRNAs regulate carpel number. Multicarpelly is normally associated with increased size of the floral meristem, and several genetic factors have been discovered that influence this characteristic. A fundamental understanding of the regulatory genes affecting carpel number can facilitate strategies for agricultural yield improvement, which is crucial, given that the global population is growing rapidly.