Publications by authors named "S Cavun"
Article Synopsis
- Familial Mediterranean Fever (FMF) is a hereditary illness that causes fever, stomach pain, and joint swelling, and colchicine is the main treatment but doesn’t cure it.
- In a study, they looked at blood samples from 50 people, including healthy individuals and those with active or inactive FMF, to measure certain markers tied to the disease.
- The results showed that some markers were higher in patients having FMF attacks compared to healthy people and those in remission, suggesting these markers could help in finding new ways to diagnose and treat FMF.
This study aimed to investigate the roles of α9β1 integrin and its ligands in Behçet's disease (BD) by examining serum levels and gene expressions. 15 healthy controls and 30 BD patients (14 active and 16 inactive) were included in the study. Serum levels of ITGA9, ITGB1, TNC, OPN, VCAM-1, VEGF, TSP1, TGM2, Emilin-1, and vWF, were measured by ELISA.
View Article and Find Full Text PDFObjectives: The main goal of the study was to investigate how pregabalin (PGB) affects proinflammatory cytokine release in patients with fibromyalgia syndrome (FMS).
Patients And Methods: This experimental research study was conducted with 85 female participants (mean age: 49.6±10.
Background: Immune system has an important effect on pain-related disorders such as fibromyalgia syndrome (FMS). There is no specific laboratory technique for the diagnosis of FMS, but measuring serum proinflammatory cytokines may help.
Objective: The purpose of our study was to determine the serum levels of immune mediators and their relationship with FMS symptoms.
Clinical intervention of pain is often accompanied by changes in affective behaviors, so both assays of affective and sensorial aspects of nociception play an important role in the development of novel analgesics. Although positive allosteric modulation (PAM) of α7 nicotinic acetylcholine receptors (nAChRs) has been recognized as a novel approach for the relief of sensorial aspects of pain, their effects on affective components of pain remain unclear. Therefore, we investigated whether PAM-4, a highly selective α7-nAChR PAM, attenuates inflammatory and neuropathic pain, as well as the concomitant depressive/anxiety comorbidities.
View Article and Find Full Text PDF