Background: Currently, the diagnosis of Alzheimer's disease dementia (ADD) is determined based on clinical criteria, as well as specific imaging and cerebrospinal fluid (CSF) biomarker profiles. However, healthcare professionals face a variety of challenges that hinder their application, such as the interpretation and integration or large amounts of data derived from neuropsychological assessment, the importance attributed to each source of information and the impact of unknown variables, among others. Therefore, this research focuses on the development of a computerized diagnostic tool based on Artificial Intelligence (AI), to strengthen the capacity of healthcare professionals in the identification and diagnosis of ADD.
View Article and Find Full Text PDFAims: Patients with D-transposition of the great arteries (D-TGA) and atrial switch experience late morbidity and mortality related to atrial arrhythmias and systemic right ventricular (SRV) failure. We sought to analyze the influence of atrial arrhythmias on long-term outcomes in this group.
Methods: A retrospective review of all patients with D-TGA and atrial switch followed at a tertiary care center was performed.
Formamide (NHC(O)H) has been observed both in the interstellar medium (ISM), being identified as a potential precursor of prebiotic molecules in space, and in the Earth's atmosphere. In these environments where temperature is very distinct, hydroxyl (OH) radicals may play an important role in the degradation of NHC(O)H. Thus, in this work, we report for the first time the experimental study of the temperature dependence of the gas-phase removal of OH in the presence of NHC(O)H over the 11.
View Article and Find Full Text PDF