Electroencephalographic and Epilepsy Findings in ZNF711 Variants: A Case Series of Two Siblings.

Background/objectives: ZNF711(Zinc finger protein 711) encodes a zinc finger protein of currently undefined function, located on the X chromosome. Current knowledge includes a limited number of case reports where this gene has been exclusively associated with X-linked intellectual disability (XLID). As far as we are aware, we report the first cases of epilepsy associated with this particular variant.

Dietary Interventions in Heart Failure With Preserved Ejection Fraction: A Scoping Review.

Patients with heart failure with preserved ejection fraction (HFpEF) are burdened by multiple diet-sensitive comorbidities, including obesity and malnutrition. Despite this, a low percentage of patients with HFpEF have been enrolled in dietary intervention trials in heart failure and few dietary interventions have been conducted in HFpEF exclusively. This scoping review will examine available evidence regarding dietary interventions in patients with HFpEF, highlight existing gaps in knowledge, and discuss emerging dietary therapies in this population.

Validity of the Actigraph-GT9X accelerometer for measuring steps and energy expenditures in heart failure patients.

Introduction: The ActiGraph (AG) accelerometer is widely used to assess physical activity (PA) in heart failure (HF) patients. However, the validity of the AG in this population remains unexplored.

Objective: Therefore, this study examined the criterion validity of the AG-GT9X for measuring step counts (SC) and energy expenditure (EE) among HF patients.

Association of creatinine-to-cystatin C ratio with computed tomography measures of skeletal muscle quantity and quality: The multi-ethnic study of atherosclerosis.

Background & Aims: Skeletal muscle (SM) health has significant prognostic value in geriatric and chronic disease populations, yet its assessment is frequently omitted due to challenges in evaluation. The creatinine-to-cystatin C ratio (CCR) is a simple serum-based measure that associates well with measured SM quantity (myopenia) and strength, but evidence for its association with SM quality (myosteatosis) is limited and conflicting. This study investigated the association between CCR and computed tomography (CT) measures of myopenia and myosteatosis.

Sex and Gender Differences in Weight-Related Biopsychosocial Factors Among Adults Receiving Buprenorphine for Opioid Use Disorder.

Introduction: Medication for opioid use disorder (MOUD) is the most efficacious treatment for opioid use disorder (OUD). MOUD uptake and continuation may be impacted by health concerns, including weight gain, and social factors, such as food insecurity, that vary between men and women. This study aimed to describe sex and gender differences in body mass index (BMI) and weight-related demographic, psychosocial, and clinical characteristics among adults receiving buprenorphine for OUD.