Publications by authors named "S Capriello"
Article Synopsis
- CD20 T cells, making up about 5% of T lymphocytes, are linked to higher production of inflammatory cytokines IL-17A and IFN-γ, and may contribute to autoimmune disorders, especially Hashimoto's thyroiditis (HT) in this study.
- The research involved 65 HT patients—some with only HT and others with associated disorders, plus 20 healthy donors as a control group, using blood samples analyzed with flow cytometry to study CD20 T cell behavior.
- Results indicated that CD20 T cell percentages were notably higher in autoimmune patients compared to healthy individuals, particularly in those with associated chronic atrophic gastritis, suggesting a potential role in
In recent years, a growing number of studies have examined the relationship between thyroid pathophysiology and intestinal microbiota composition. The reciprocal influence between these two entities has been proven so extensive that some authors coined the term "gut-thyroid axis". However, since some papers reported conflicting results, several aspects of this correlation need to be clarified.
View Article and Find Full Text PDFStudies analyzing the relationship between microbiota composition and the thyroid have been increasing rapidly in recent years, and evidence has recently come to light about the involvement of the gut microbiota in various aspects of thyroid pathology. Recently, besides studies analyzing the microbiota composition of different biological niches (salivary microbiota or thyroid tumor microenvironment) in patients with thyroid disorders, some studies have been carried out in peculiar subcategories of patients (pregnant women or obese). Other studies added a metabolomic insight into the characterization of fecal microflora in an attempt to enlighten specific metabolic pathways that could be involved in thyroid disorder pathogenesis.
View Article and Find Full Text PDFThe relationship between thyroid disorders and vitamin A.: A narrative minireview.
Front Endocrinol (Lausanne)
October 2022
The terms "vitamin A" and "retinoids" encompass a group of fat-soluble compounds essential for human nutrition. Some of them (retinol, retinal, 9-cis-retinoic acid, tretinoin, and 13-cis-retinoic acid) are fully natural, while others are synthetic compounds used mostly for therapeutic purposes. Some evidence indicates that the nutritional status of these retinoids (i.
View Article and Find Full Text PDFDaily requirement of softgel thyroxine is independent from gastric juice pH.
Front Endocrinol (Lausanne)
October 2022
Background: Softgel levothyroxine (LT4) preparation showed a better dissolution profile at increasing pH as compared to tablet LT4 preparation. Clinical studies suggested a better performance of softgel LT4 preparation in patients with gastric disorders but whether this finding is related to gastric juice pH variation is not known.
Methods: Twenty-eight hypothyroid patients (24F/4M; median age=50 treated with tablet LT4 (median dose= 1.