Publications by authors named "S Cantara"
Purpose: It was demonstrated that differentiated thyroid cancer (DTC) patients may develop multiple primary tumors (MPT) during follow-up. Many studies showed an association between reduced telomere length and cancer phenotype; in particular, the short telomeres were associated with the development of a primary tumor. However, the role of altered telomere length in MPT development has not yet been demonstrated.
View Article and Find Full Text PDFPurpose: An increase of IGF-1 has been reported during therapy with dopamine agonists (DA) for prolactinomas; in such cases a correct diagnosis is pivotal to avoid an unnecessary reduction or withdrawal of DA, which are needed to maintain normal prolactin levels. This study was aimed to measure IGF-1 levels, at baseline and during follow-up, in a cohort of patients with prolactinoma, treated with cabergoline, stratified by body mass index.
Methods: We retrospectively enrolled 35 patients (15 F/20 M; age m ± SD, years: 43.
Article Synopsis
- * In a study of 2,536 young athletes under 40 with no cardiac history, advanced AVB prevalence was found to be about 0.1%, increasing to 2% in highly trained males; all cases of advanced AVB tested positive for anti-Ro/SSA antibodies.
- * Laboratory tests revealed that immunoglobulin G from athletes with anti-Ro/SSA antibodies inhibited calcium current and reduced calcium channel expression, linking these antibodies directly to
Pollen, the male gametophyte of seed plants, is extremely sensitive to UV light, which may prevent fertilization. As a result, strategies to improve plant resistance to solar ultraviolet (UV) radiation are required. The tardigrade damage suppressor protein (Dsup) is a putative DNA-binding protein that enables tardigrades to tolerate harsh environmental conditions, including UV radiation, and was therefore considered as a candidate for reducing the effects of UV exposure on pollen.
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- * The most notable success is nusinersen for SMA, which improves symptoms and slows progression, while tofersen is aimed at ALS but hasn't shown benefits for all patients.
- * This review summarizes current ASO research in MNDs, highlighting both successful and unsuccessful outcomes, discussing the strengths and weaknesses of existing studies, and suggesting future research directions for better treatments.