Aerosols Contamination in the Dental Practice Following Everyday Procedures: An Observational Study.

Objective: The purpose of the present observational study was to evaluate the bacterial load in the air following various dental procedures.

Methods: Air contamination following seven aerosol-generating dental procedures was assessed. The air volume was sampled by a wet cyclone collector for 10 min during 10 sessions of the following procedures: air-polishing, ultrasonic instrumentation, manual instrumentation, rubber cup polishing, cavity preparation with a 1:5 red contra-angle, cavity preparation with turbine and Low Volume Evacuator (LVE), and cavity preparation with turbine and High Volume Evacuator (HVE).

Cell damage shifts the microRNA content of small extracellular vesicles into a Toll-like receptor 7-activating cargo capable to propagate inflammation and immunity.

Background: The physiological relevance of cell-to-cell communication mediated by small extracellular vesicle-encapsulated microRNAs (sEV-miRNAs) remains debated because of the limiting representativity of specific miRNAs within the extracellular pool. We hypothesize that sEV-miRNA non-canonical function consisting of the stimulation of Toll-like receptor 7 (TLR7) may rely on a global shift of the sEV cargo rather than on the induction of one or few specific miRNAs. Psoriasis represents an ideal model to test such hypothesis as it is driven by overt activation of TLR7-expressing plasmacytoid dendritic cells (pDCs) following keratinocyte damage.

Clinical Comparison of Guided Biofilm Therapy and Scaling and Root Planing in the Active Phase of Periodontitis Management.

Objective:  The aim of this randomized, controlled, split-mouth study was to compare full-mouth air polishing followed by ultrasonic debridement (known as Guided Biofilm Therapy [GBT]) versus traditional Scaling and Root Planing (SRP), in terms of pocket closure in patients with stages III and IV periodontitis.

Materials And Methods:  The patients underwent periodontal therapy in two sessions. At the beginning of the first session, quadrants I and IV and II and III were randomly assigned to GBT or SRP treatment.

Circulating Serum Micro-RNA as Non-Invasive Diagnostic Biomarkers of Endometriosis.

Background/objectives: Endometriosis (END) is a painful gynecological condition. Clinical examination, imaging, and laparoscopy can provide a definitive diagnosis of END. Nonetheless, non-invasive biomarkers could help enhance and streamline the diagnostic process.