Publications by authors named "S Calaforra"
Article Synopsis
- PM-allergoids are new vaccines designed to target dendritic cells and induce Treg cells, with this study focusing on their safety and optimal dosage for treating house dust mite allergies in humans.
- In a clinical trial with 196 participants, doses of PM-HDM were compared against placebos using various administration routes (subcutaneous and sublingual) over four months, measuring key outcomes like nasal provocation tests and symptom scores.
- Results showed that PM-HDM was safe, with significant improvements in allergy symptoms observed at higher doses, particularly at 3000 mTU for sublingual administration and 5000 mTU for subcutaneous administration.
Recurrent wheezing in children represents a severe public health concern. Wheezing attacks (WA), mainly associated with viral infections, lack effective preventive therapies. To evaluate the efficacy and safety of mucosal sublingual immunotherapy based on whole inactivated bacteria (MV130) in preventing WA in children.
View Article and Find Full Text PDFTreatment of Anaphylaxis to Rocuronium with Sugammadex: A Case Report with Bronchospasm as the Only Symptom.
Turk J Anaesthesiol Reanim
February 2019
Anaphylaxis during anaesthesia is a rare event occurring in up to 1:20,000 anaesthetics and in 33%-63% neuromuscular blocking agents are involved. Several case reports suggested the effectiveness of sugammadex in the treatment of rocuronium-induced anaphylactic shock refractory to conventional treatment. We report a case of anaphylactic reaction to rocuronium that caused isolated respiratory symptoms and showed no improvement in oxygen saturation after intravenous corticosteroids and intratracheal beta-2 agonists and that was successfully treated with sugammadex.
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