In-vitro study on type I collagen synthesis in low-level laser therapy on the early ligament fibroblasts' healing process.

Background: Low-level Laser Therapy (LLLT) has demonstrated its potential in promoting fiber matrix maturation, collagen synthesis, and fibroblast proliferation, contributing to tissue regeneration. Our study aimed to investigate the impact of LLLT on collagen type I synthesis, cell proliferation, and viability in human ligament fibroblasts derived from the Anterior Cruciate Ligament (ACL).

Methods: Tissue samples were obtained from individuals undergoing arthroscopic ACL reconstruction surgery.