[Development of serum cholesterol and frequency of hypercholesterolemia in children and adolescents: results of the Berlin-Pankow cohort study].

The age-related evolution of serum cholesterol has been studied in a cohort of 475 boys and girls born in 1964, living in Berlin-Pankow district; they have been followed up from age 13-14 to 20-21 (response rate after eight years: 66%). At age 13-14, mean total cholesterol was higher among boys (183 +/- 34 mg/dl) as well as among girls (187 +/- 33 mg/dl) as compared with those observed in other populations. About one third of the subjects at this age had values greater than 200 mn/dl.

[Learning and chronobiological regulation following experimental damage to the coronary-artery wall of albino rats].

Forty male albino rats were used to study the relationship between experimentally (concentrated hydrochloric acid) produced local structural changes of the coronary artery wall and central nervous information processing and chronobiological events, respectively. The alterations of the coronary arteries caused by this treatment did not produce infarction but initiated on the whole length of the arterial branch proliferative processes that are complete within 12 weeks following the intervention. Central nervous information processing and chronoregulatory processes showed, immediately after exposure to hydrochloric acid, pronounced malfunctions followed by a stage of hyperreactivity (4 weeks following the damage).