Publications by authors named "S C Waller"

Significance: In an aging population, the number of people living with neurodegenerative disease is projected to increase. It is vital to develop reliable, noninvasive biomarkers to detect disease onset and monitor progression, and there is a growing body of research into the ocular surface as a potential source of such biomarkers.

Background: This article reviews the potential of in vivo corneal confocal microscopy and tear fluid analysis as tools for biomarker development.

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Article Synopsis
  • Population density is crucial for wildlife management, particularly in the Russian Far East, where methods like the FMP snow tracking are used to estimate ungulate densities and support Amur tiger conservation.
  • Despite the effectiveness of FMP, reliability issues due to climate change and survey design challenges prompt the exploration of camera traps as an alternative for monitoring prey density, though their potential is still largely untested.
  • A comparative study over three years found that, while both FMP and camera trap methods provided similar prey density estimates, discrepancies in prey biomass calculations highlight the need for caution in management decisions and suggest more research is necessary to improve estimation methods.
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Introduction: Changing health care requires changing medical education. In this position paper it is suggested that subsequent innovations in medical education each had their specific strengths and shortcomings. What they have, however, in common is that they place the medical student and their competencies at their center.

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  • - Germinal matrix hemorrhage (GMH) is a serious condition in preterm infants linked to blood vessel rupture in the brain, but the reasons behind this vulnerability are not well understood.
  • - Research shows that microglia (immune cells in the brain) interact with developing blood vessels differently as the brain matures and their absence can hinder blood vessel growth in key brain areas.
  • - In preterm infants with GMH, immune cells show abnormal activation, leading to inflammation and factors that compromise blood vessel integrity, suggesting that the immune response plays a crucial role in the development of GMH.
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