Publications by authors named "S C Thust"
Article Synopsis
- Diffusion-weighted imaging (DWI) is a method used in brain tumor surgeries with intraoperative MRI, but traditional techniques like echo planar imaging (EPI-DWI) can suffer from image distortions and artifacts.
- This study compares EPI-DWI and a less distorted technique known as turbo spin echo DWI (TSE-DWI) to see which one radiologists prefer during surgery.
- Results indicate that TSE-DWI performs equally or better than EPI-DWI in terms of image quality, particularly in reducing distortions and artifacts, making it a better option for intraoperative imaging.
Background: Isocitrate Dehydrogenase 1/2 (IDH 1/2)-wildtype (WT) astrocytomas constitute a heterogeneous group of tumors and have undergone a series of diagnostic reclassifications over time. This study aimed to investigate molecular markers, clinical, imaging, and treatment factors predictive of outcomes in WHO grade 2/3 IDH-WT astrocytomas ('early glioblastoma').
Methodology: Patients with WHO grade 2/3 IDH-WT astrocytomas were identified from the hospital archives.
Article Synopsis
- A study aimed to use deep learning on brain MRI scans to predict 8-month survival rates for glioblastoma patients after radiotherapy, involving data from 206 patients diagnosed across UK centers.
- The model's performance was tested against both imaging data (from MRI scans) and non-imaging data (like demographics) and showed high accuracy, particularly with imaging data outperforming non-imaging data.
- This deep learning model can help identify glioblastoma patients at higher risk of early mortality, potentially guiding them towards early second-line treatments or clinical trials.
Primary Central Nervous System Lymphoma (PCNSL) is a highly malignant brain tumour. We investigated dynamic changes in tumour volume and apparent diffusion coefficient (ADC) measurements for predicting outcome following treatment with MATRix chemotherapy in PCNSL. Patients treated with MATRix ( = 38) underwent T1 contrast-enhanced (T1CE) and diffusion-weighted imaging (DWI) before treatment, after two cycles and after four cycles of chemotherapy.
View Article and Find Full Text PDFIntroduction: Gliomatosis cerebri describes a rare growth pattern of diffusely infiltrating glioma. The treatment options are limited and clinical outcomes remain poor. To characterise this population of patients, we examined referrals to a specialist brain tumour centre.
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