A dataset of Antarctic ecosystems in ice-free lands: classification, descriptions, and maps.

Antarctica, Earth's least understood and most remote continent, is threatened by human disturbances and climate-related changes, underscoring the imperative for biodiversity inventories to inform conservation. Antarctic ecosystems support unique species and genetic diversity, deliver essential ecosystem services and contribute to planetary stability. We present Antarctica's first comprehensive ecosystem classification and map of ice-free lands, which host most of the continent's biodiversity.

Global comparison of the economic costs of coronary heart disease: a systematic review and meta-analysis.

Objectives: Coronary heart disease (CHD) is the leading cause of global morbidity and mortality, yet no comprehensive evaluation of its global economic costs exists. We conducted a systematic review with meta-analysis to examine the costs of CHD treatment by region and CHD subtypes, examine whether there are cost difference by sex, and examine costing methodologies.

Design: We conducted a systematic review and meta-analysis of non-randomised studies.

Engaging health system, service and consumer representatives in the co-design of a multi-criteria decision-making framework for commissioning overweight and obesity programs and services.

Background: Obesity is a multi-faceted problem that requires complex health system responses. While no single program or service is sufficient to meet every individual's needs, some criteria that increase the likelihood of program/service quality delivery to produce effective outcomes exist. However, although research on health commissioning is available internationally and is growing within the Australian context, no evidence exists of a multi-criteria decision-making framework to address the complexity required for effective commissioning of overweight and obesity early intervention and weight management programs or services.

Machine Learning Reveals Signatures of Promiscuous Microbial Amidases for Micropollutant Biotransformations.

Organic micropollutants, including pharmaceuticals, personal care products, pesticides, and food additives, are widespread in the environment, causing potentially toxic effects. Human waste is a direct source of micropollutants, with the majority of pharmaceuticals being excreted through urine. Urine contains its own microbiota with the potential to catalyze micropollutant biotransformations.