Publications by authors named "S C Regueme"

Article Synopsis
  • The study aimed to develop a prediction model to identify mild COVID-19 patients at risk of worsening, utilizing clinical, biological, and chest CT data.
  • It involved training and validating the model across multiple hospitals, incorporating factors like age, gender, and lymphocyte counts alongside CT scan analysis.
  • Results indicated that combining CT scan quantification and radiomics with clinical parameters significantly improved prediction accuracy for identifying patients likely to develop more severe COVID-19.*
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An altered amino acid metabolism has been described in frail older adults which may contribute to muscle loss and functional decline associated with frailty. In the present investigation, we compared circulating amino acid profiles of older adults with physical frailty and sarcopenia (PF&S, = 94), frail/pre-frail older adults with type 2 diabetes mellitus (F-T2DM, = 66), and robust non-diabetic controls ( = 40). Partial least squares discriminant analysis (PLS-DA) models were built to define the amino acid signatures associated with the different frailty phenotypes.

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Article Synopsis
  • Tranexamic acid (TXA) after cesarean delivery may reduce blood loss and transfusions, but it doesn’t significantly help with other hemorrhage-related issues, making its routine use uncertain.
  • The study aimed to see if TXA is effective in preventing blood loss specifically for women with multiple pregnancies undergoing cesarean deliveries.
  • Results showed no significant difference in blood loss between women receiving TXA and those on placebo, indicating that TXA may not be beneficial in this high-risk group.
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Introduction: Frail older people with diabetes often present with or develop walking impairments, in part due to lower-limb sensory-motor neuropathy. Several studies suggest a possible improvement of balance control using somatosensory stimulation. We undertook a novel randomized control trial, the aim of which was to observe whether use of this device for 1 month improves walking speed as measured in the 10-m fast walking speed test standardized to body size at month 1 (M1) (FWS).

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Objectives: Type 2 diabetes (T2D) is a risk factor of frailty and cognitive impairment. Impaired gait in older people is associated with incident vascular dementia. We aimed to assess whether in frail or prefrail older subjects with T2D, lower gait speed can be associated with faster cognitive decline.

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