Publications by authors named "S C Maheshwari"
Barrett's Esophagus (BE) is the only known precursor for esophageal adenocarcinoma (EAC). Patients with multiple risk factors for BE/EAC are recommended for screening; however, few eligible patients undergo evaluation by endoscopy. EsoGuard (EG) is a commercially available biomarker assay used to analyze esophageal cells collected non-endoscopically with EsoCheck (EC) for the qualitative detection of BE/EAC.
View Article and Find Full Text PDFIntracerebral haemorrhage (ICH) is the most severe subtype of stroke, with a 2-year mortality of nearly 50% and the greatest rate of disability amongst stroke survivors. Whilst treatment options for ICH remain limited, the condition requires prompt identification and rapid intervention to reduce permanent brain damage, with diagnosis traditionally confirmed by CT imaging. Although imaging is excellent at determining the presence of an intracranial bleed, biomarkers may help to identify the type of stroke or when the stroke began.
View Article and Find Full Text PDFRationale: Early mortality in intracerebral hemorrhage (ICH) is due to hematoma volume (HV) expansion, and there are no effective treatments available other than reduction in blood pressure. Tranexamic acid (TXA) a hemostatic drug that is widely available and safe can be a cost-effective treatment for ICH, if proven efficacious.
Hypothesis: Administration of TXA in ICH patients when given within 4.
Article Synopsis
- The study focuses on how otolaryngologists approach testing for congenital sensorineural hearing loss, specifically looking at cCMV infection and genetic testing methods.
- A survey of 20 otolaryngologists showed that 90% use cCMV and genetic tests, with 95% applying cCMV testing in their practices, and many pursue broader genetic screening if initial tests return negative.
- The findings also highlight reimbursement rates for these tests, revealing that a majority of respondents receive coverage for cCMV, genetic variant testing, and wider genetic screening.
Progressive Unilateral Foot Drop in a Child due to Neuromuscular Choristoma.
Ann Indian Acad Neurol
September 2024
An 8.5-year-old boy presented with a history of progressive unilateral foot drop. A contrast magnetic resonance imaging of the pelvic girdle and the lumbosacral plexus revealed a diffuse fusiform thickening of the right lumbosacral trunk and the sciatic nerve in the intrapelvic and gluteal regions, with findings characteristic of a choristoma.
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