Biologic Therapy in Pediatric Chronic Rhinosinusitis: A Systematic Review.

Objective: Provide clinicians with current evidence for biologic therapy in children with chronic rhinosinusitis with nasal polyposis (CRSwNP).

Data Sources: PubMed, MEDLINE, Cochrane, and clinical trial registries.

Review Methods: Key search terms related to biologic therapy in pediatric CRSwNP were identified via a structured query of current medical literature and clinical trial databases.

Pediatric Foreign Body Aspiration: Time of Occurrence and Factors Affecting Outcomes.

Objectives: The goal of this study was to assess which factors could affect outcomes in pediatric patients undergoing bronchoscopy for foreign body aspiration (FBA).

Methods: This is a retrospective case series study evaluating patients who underwent bronchoscopies because of FBA at a tertiary pediatric hospital between January 1, 2010, and December 6. 2018.

Undifferentiated recurrent fevers in pediatrics are clinically distinct from PFAPA syndrome but retain an IL-1 signature.

Autoinflammatory disorders of the innate immune system present with recurrent episodes of inflammation often beginning in early childhood. While there are now more than 30 genetically-defined hereditary fever disorders, many patients lack a clear diagnosis. Many pediatric patients are often grouped with patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome despite failing to meet diagnostic criteria.

Psychometric Evaluation of the Nasal Obstruction Symptom Evaluation Scale for Pediatric Patients.

Objective: To evaluate the psychometric properties of the nasal obstruction symptom scale within a sample of pediatric patients undergoing septoplasty or functional septorhinoplasty.

Study Design: This was a prospective study with nasal obstruction symptom scale evaluations conducted pre- and postoperatively.

Setting: A tertiary care pediatric hospital.