Forming and compliance-free operation of low-energy, fast-switching HfOS/HfS memristors.

We demonstrate low energy, forming and compliance-free operation of a resistive memory obtained by the partial oxidation of a two-dimensional layered van-der-Waals semiconductor: hafnium disulfide (HfS). Semiconductor-oxide heterostructures are achieved by low temperature (<300 °C) thermal oxidation of HfS under dry conditions, carefully controlling process parameters. The resulting HfOS/HfS heterostructures are integrated between metal contacts, forming vertical crossbar devices.

Examining the Psychometric Network Structure of Social Anxiety: A Scoping Review.

The network approach offers a novel perspective for conceptualizing the psychopathology of social anxiety disorder (SAD). This scoping review aimed to map the existing literature on the psychometric network structures of social anxiety symptoms and identify future research directions. A total of 61 studies were identified through searches in PubMed, PsycINFO, ScienceDirect, Cochrane Library, ClinicalTrials.

A Network Control Theory of Dynamic Systems Approach to Personalize Therapy.

Contemporary latent disease models of psychopathology have shown limited clinical utility and the efficacy of conventional treatments have been disappointing. An alternative approach offers the network approach and a dynamic systems perspective to psychopathology and treatment change. To understand and modify dynamic systems, engineering and mathematics have been relying on principles of network control theory.

Expanding the Chemical Space of Reverse Fosmidomycin Analogs.

Multidrug-resistant pathogens pose a major threat to human health, necessitating the identification of new drug targets and lead compounds that are not susceptible to cross-resistance. This study demonstrates that novel reverse thia analogs of the phosphonohydroxamic acid antibiotic fosmidomycin inhibit 1-deoxy-d-xylulose 5-phosphate reductoisomerase (DXR), an essential enzyme for , , and that is absent in humans. Some novel analogs with large α-phenyl substituents exhibited strong inhibition across these three DXR orthologues, surpassing the inhibitory activity of fosmidomycin.

Supported Mindfulness-Based Self-Help Intervention as an Adjunctive Treatment for Rapid Symptom Change in Emotional Disorders: A Practice-Oriented Multicenter Randomized Controlled Trial.

Introduction: Rapid symptom relief is crucial for individuals with emotional disorders. The current study aimed to determine whether facilitator-supported mindfulness-based self-help (MBSH) intervention as an adjunctive treatment could provide rapid improvement for individuals with emotional disorders.

Methods: A practice-oriented randomized controlled trial was conducted on a sample of 302 patients with emotional disorders from four centers.