Publications by authors named "S C Gandevia"

Introduction: Lumbar transcutaneous spinal cord stimulation (TSS) evokes synchronized muscle responses, termed spinally evoked motor response (sEMR). Whether the structures TSS activates to evoke sEMRs differ when TSS intensity and waveform are varied is unknown.

Methods: In 15 participants (9F:6M), sEMRs were evoked by TSS over L1-L3 (at sEMR threshold and suprathreshold intensities) using conventional (one 400-µs biphasic pulse) or high-frequency burst (ten 40-µs biphasic pulses at 10 kHz) stimulus waveforms in vastus medialis (VM), tibialis anterior (TA) and medial gastrocnemius (MG) muscles.

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  • The study investigated how well different age groups and individuals with COPD can detect and perceive breathing resistance during simulated loads, emphasizing the importance for airway protection and breathlessness management.
  • It involved 18 participants with COPD, 17 older adults, and 23 young adults, comparing their ability to detect changes in airway resistance and their perceived effort while breathing.
  • Findings showed that older adults had a steeper relationship between perceived effort and resistance compared to younger adults, suggesting that they may experience greater difficulty in respiratory effort due to increased awareness of breathing resistance, especially at higher loads.
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Study Design: Single centre training study.

Objectives: To investigate, in a group of people with spinal cord injury (SCI), the effect of transcutaneous functional electrical stimulation of the abdominal muscles (abdominal FES) during cough training on blood pressure (BP), and how it is affected by injury characteristics and alters over time.

Setting: Laboratory and community.

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Transcutaneous electrical stimulation with repetitive bursts of a kilohertz carrier frequency is thought to be less painful than conventional pulsed currents by reducing the sensitivity of pain receptors. However, no purported benefit has been shown unequivocally. We compared the effects of carrier-frequency stimulation and conventional stimulation on pain tolerance and the thresholds for sensory and motor axons in twelve participants.

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  • Skeletal muscles are vital for movement, and understanding how to estimate the forces they produce is essential in fields like biomechanics, robotics, and rehabilitation.
  • Direct measurement of muscle force in humans is invasive, so non-invasive methods like electromyography (EMG) are used for estimation, and a matrix developed by CEDE provides guidelines on EMG applications.
  • The matrix suggests EMG methods for identifying muscle force during isometric and dynamic contractions, while emphasizing the importance of considering various factors to improve accuracy in estimating muscle forces, fostering interdisciplinary discussions to enhance muscle modeling techniques.
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