Publications by authors named "S C Evins"
Article Synopsis
- Increased mechanical forces on developing cardiac valves influence the formation of the extracellular matrix (ECM), which is crucial for tissue integrity and cellular signaling.
- The study focused on the pulmonary valve (PV) during a key developmental period from birth to postnatal day 7, analyzing the impact of blood flow on mechanical loading.
- Findings demonstrated that in mice lacking the proteoglycan protease ADAMTS5, the PV showed temporary phenotypic improvement and changes in proteoglycan localization, suggesting that increased blood flow activates ECM proteases that help organize ECM layers essential for cardiac valve maturation.
Iatrogenic prostatorectal fistula is a rarely seen urologic complication of transurethral resection of the prostate and stricture dilatation with sounds. In the past, such cases have been managed with colostomy diversion of the fecal stream and suprapubic cystostomy diversion of the urinary stream and in most cases operative closure of the fistula. This case illustrates that a more conservative nonoperative approach can lead to successful closure of such a fistula in selected cases.
View Article and Find Full Text PDFTen cases of urinary extravasation from the male urethra are reviewed. Parameters include etiology, symptoms, diagnosis, treatment, and complications. Prognosis may be predicted by extent of extravasation, associated disease states, and presence of shock.
View Article and Find Full Text PDFThe management of severe renal lacerations produced by blunt trauma requires accurate diagnosis and close followup. All severe renal lacerations cannot be treated expectantly and non-operatively. However, in the stable patient with an accurately defined lesion and no other injury requiring surgical intervention a non-operative approach appears to be acceptable.
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