Publications by authors named "S C Esteves"
Fertil Steril
November 2024
Article Synopsis
- - The study aimed to identify serum anti-Müllerian hormone (AMH) and antral follicle count (AFC) thresholds that signal a higher risk of hyper-response to ovarian stimulation in women undergoing their first IVF cycle, following the HERA definition.
- - A total of 4220 women were analyzed, revealing thresholds of AMH≥4.38ng/mL and AFC≥16 for the overall cohort, with varying thresholds based on age groups.
- - The findings highlighted that factors like AMH, AFC, and age significantly predict the likelihood of hyper-response during ovarian stimulation, with older women requiring more hormonal treatment.
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J Assist Reprod Genet
November 2024
Article Synopsis
- This study investigates whether daily subcutaneous administration of 25 mg progesterone improves the chances of live birth in women with low serum progesterone levels (7-10 ng/mL) before a frozen embryo transfer (FET).
- A cohort of 192 women was divided into three groups based on their progesterone levels and whether they received the rescue treatment, with the main focus on comparing live birth rates (LBR) among these groups.
- The results showed that the live birth rates were similar across the groups, indicating that adding the progesterone rescue treatment does not significantly improve outcomes for patients with low serum progesterone levels.
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J Assist Reprod Genet
October 2024
Article Synopsis
- This study explores how the daily dose of follicle-stimulating hormone (FSH) impacts the chances of suboptimal ovarian response during IVF, specifically using POSEIDON's criteria.
- It examines a group of 4005 women with normal hormone levels undergoing their first IVF/ICSI cycle, assessing whether varying FSH doses (≤300 IU vs >300 IU) influence the retrieval of 4-9 oocytes.
- Results show that increasing the FSH dose did not decrease the risk of suboptimal response, while factors like female age, and hormone levels were found to be significant predictors instead.
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Reprod Biol Endocrinol
October 2024
Article Synopsis
- A panel of international experts evaluated and discussed the POSEIDON criteria, aiming to improve management strategies for women with low prognosis in assisted reproductive technology (ART).
- Through a Delphi consensus process involving multiple rounds of voting, 53 experts reviewed 17 statements and reached consensus on their relevance for patient care and outcomes in ART.
- Key recommendations include using specific treatments and tools to enhance success rates, while emphasizing the need for more large-scale studies to validate existing findings.
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