Publications by authors named "S C De Greeff"
Background: At the beginning of the COVID-19 pandemic in 2020, little was known about the spread of COVID-19 in Dutch nursing homes while older people were particularly at risk of severe symptoms. Therefore, attempts were made to develop a nationwide COVID-19 repository based on routinely recorded data in the electronic health records (EHRs) of nursing home residents. This study aims to describe the facilitators and barriers encountered during the development of the repository and the lessons learned regarding the reuse of EHR data for surveillance and research purposes.
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- The study explores the relationship between antimicrobial use (AMU) in livestock and antimicrobial resistance (AMR) in human infections in the Netherlands from 2004 to 2020.
- It finds that while AMU in livestock is decreasing, AMR among human infections is still increasing, indicating that reducing livestock AMU alone may not effectively combat AMR in humans.
- The research highlights the need for further investigation into the genetic and evolutionary factors contributing to AMR, suggesting that a broader strategy may be needed to address this public health issue.
Article Synopsis
- The study is about asymptomatic bacteriuria (ASB) in older people, where bacteria are present in urine but don't cause symptoms of a urinary tract infection (UTI).
- Researchers believe that having non-dangerous bacteria might actually help protect the bladder from harmful bacteria that can cause UTIs.
- They will collect urine samples and health information from nursing home residents over 18 months to see how ASB relates to UTIs and if it helps prevent them.
Background: Although older people in nursing homes have a larger susceptibility to infectious diseases, the extent to which infectious diseases contribute to their mortality is unknown. Therefore, we quantified the associations between seasonal infectious diseases and all-cause mortality in Dutch nursing homes.
Methods: We analyzed time series (January 2009 to December 2021) of the weekly sentinel surveillance of infectious diseases in Dutch nursing homes.
Association between antimicrobial usage in livestock and antimicrobial resistance in Escherichia coli isolates from human urinary tract infections in the Netherlands, 2009-2020.
J Antimicrob Chemother
October 2024
Background: In the last decade, veterinary antimicrobial usage (AMU) and antimicrobial resistance (AMR) among indicator bacteria in livestock have decreased substantially in the Netherlands. The extent to which this decrease has affected AMR levels among human infections remains unclear.
Objectives: To assess the association between AMU in livestock and AMR in Escherichia coli isolates from human urinary tract infections (UTIs).