The cannabinoid 2 receptor agonist β-caryophyllene modulates the inflammatory reaction induced by Mycobacterium bovis BCG by inhibiting neutrophil migration.

Objective And Design: β-Caryophyllene (BCP) is a sesquiterpene that binds to the cannabinoid 2 (CB) receptor and exerts anti-inflammatory effects. In this study, we investigated the anti-inflammatory effect of BCP and another CB agonist, GP1a in inflammatory experimental model induced by Mycobacterium bovis (BCG).

Methods: C57Bl/6 mice were pretreated orally with BCP (0.

The allergic inflammatory reaction in neonatal streptozotocininduced diabetic rats: evidence of insulin resistance and microvascular dysfunction.

Objective: To investigate the allergic reaction in neonatal streptozotocin (nSTZ)-induced diabetes mellitus.

Material: Male newborn Wistar rats were made diabetic by the injection of streptozotocin (160 mg/kg, i. p.

The anti-allergic activity of the acetate fraction of Schinus terebinthifolius leaves in IgE induced mice paw edema and pleurisy.

Schinus is a genus of the Anacardiaceae family and contains Schinus terebinthifolius, the Brazilian pepper tree that is widely used in folk medicine. We investigate the anti-allergic activity of the ethyl acetate fraction of S. terebinthifolius Raddi (ST fraction).

Pharmacological study of anti-allergic activity of Syzygium cumini (L.) Skeels.

Myrtaceae is a plant family widely used in folk medicine and Syzygium and Eugenia are among the most important genera. We investigated the anti-allergic properties of an aqueous leaf extract of Syzygium cumini (L.) Skeels (SC).

Down-regulation of mast cell activation and airway reactivity in diabetic rats: role of insulin.

Hormones play a modulating role in allergic inflammation. An inverse relationship between atopy and diabetes mellitus was reported. The mechanisms regulating this interaction are not completely understood.