Learning tracheal intubation with a hyperangulated videolaryngoscopy blade: sub-analysis of a randomised controlled trial.

Introduction: The number of tracheal intubation attempts required to reach proficiency in videolaryngoscopy with hyperangulated blades is unknown. Understanding this training requirement might guide training for clinicians who perform laryngoscopy. We therefore performed a planned sub-analysis of a randomised controlled trial comparing tracheal intubation success with videolaryngoscopy vs.

The Need for More Learning Opportunities in Real-Time Ultrasonography for Undergraduate Medical Students: A Call for Pre-clerkship Electives.

Medical education is at a point of transition in which it must reform to meet the demand of healthcare providers competent in ultrasonography. This article recommends the pre-clerkship elective infrastructure as a method for medical schools to begin prototyping content and modes of delivering ultrasound education. Doing so will prepare medical students earlier in their careers to use and build upon their knowledge of ultrasound during clerkships and as residents.

Fertility protection during chemotherapy treatment by boosting the NAD(P) metabolome.

Chemotherapy induced ovarian failure and infertility is an important concern in female cancer patients of reproductive age or younger, and non-invasive, pharmacological approaches to maintain ovarian function are urgently needed. Given the role of reduced nicotinamide adenine dinucleotide phosphate (NADPH) as an essential cofactor for drug detoxification, we sought to test whether boosting the NAD(P) metabolome could protect ovarian function. We show that pharmacological or transgenic strategies to replenish the NAD metabolome ameliorates chemotherapy induced female infertility in mice, as measured by oocyte yield, follicle health, and functional breeding trials.

Tensionable lesser tuberosity osteotomy repair for anatomic total shoulder arthroplasty.

A lesser tuberosity osteotomy (LTO) is commonly performed during total shoulder arthroplasty to access the glenohumeral joint. Healing of the LTO is critical to optimizing the outcome of the procedure and is enhanced by a repair that provides stability and compression across the osteotomy site. The purpose of this article is to describe a technique that uses a tensionable suture construct to repair the LTO during anatomic total shoulder arthroplasty using a stemless humeral component.