Publications by authors named "S Burce Ozler"
Article Synopsis
- * Research indicates that the rhoA/rho-kinase pathway, which is activated by gentamicin, contributes to kidney damage similar to that seen in diabetes and renal ischemia.
- * The study shows that administering the antioxidant alpha-linolenic acid (ALA) alongside gentamicin to mice reduced the damaging effects on the Rho/Rho-kinase pathway, suggesting that oxidative stress plays a key role in gentamicin-induced nephrotoxicity.
The role of the Chitinase 3-Like 1 (CHI3L1) genes in the preeclampsia pathophysiology.
Rev Assoc Med Bras (1992)
July 2024
Objective: The aim of this study was to investigate the relationship between Chitinase 3-Like 1 gene polymorphisms and the occurrence of preeclampsia in a selected cohort of pregnant women.
Methods: A total of 75 pregnant women participated in the study, 35 of whom were diagnosed with preeclampsia, while 40 served as healthy controls. The preeclamptic group was subdivided based on severity.
Purpose: We aimed to investigate maternal thyroid parenchymal vascularity with 2-dimensional color superb microvascular imaging vascularization index (2D-cSMIVI) levels and thyroid gland volume in the first, second and third trimesters.
Methods: This longitudinal prospective study was carried out with participants selected from 30 healthy asymptomatic pregnant women. Ultrasonography (US) for the thyroid gland was performed in each trimester.
MicroRNA is associated with angiogenesis, invasion, proliferation, and vascular endothelial remodeling of various diseases. We aimed to investigate serum MicroRNA (miRNA) levels in preeclampsia (PE) and to determine whether any changes in miRNA levels are useful in predicting early onset preeclampsia (EOPE) and adverse perinatal outcomes. A total of 89 pregnant patients were enrolled in this prospective case-control study (55 PE and 34 healthy controls).
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