The individualisation of glycaemic targets in response to patient characteristics in type 2 diabetes: a scoping review.

Background: Evidence and guidelines increasingly support an individualised approach to care for people with type 2 diabetes and individualisation of glycaemic targets in response to patient factors.

Methods: We undertook a scoping review of the literature for evidence of factors impacting upon glycated haemoglobin target individualisation in adults with type 2 diabetes. Data were analysed thematically with the themes inductively derived from article review.

Presentation, management and outcomes in acute pituitary apoplexy: a large single-centre experience from the United Kingdom.

Objective: To study the presentation, management and outcomes and to apply retrospectively the Pituitary Apoplexy Score (PAS) (United Kingdom (UK) guidelines for management of apoplexy) to a large, single-centre series of patients with acute pituitary apoplexy.

Design: Retrospective analysis of casenotes at a single neurosurgical centre in Liverpool, UK.

Results: Fifty-five patients [mean age, 52·4 years; median duration of follow-up, 7 years] were identified; 45 of 55 (81%) had nonfunctioning adenomas, four acromegaly and six prolactinomas.

Obstetric performance of women who have previously delivered a baby of low birthweight.

Objectives: To investigate pregnancy outcomes in women who have previously given birth to a baby weighing less than 2500 grams in a population in which the low birthweight rate is high.

Methods: We compared the obstetric performance of 100 women who had delivered a low birthweight baby (<2500g) at term in a previous pregnancy (cases) with those of 100 women who were matched for age, height, body mass index at booking, parity and medical disorders, who had previously delivered a baby above that threshold (controls).

Results: We found the following significant differences between cases and controls (p<0.

Hypogonadism secondary to hyperprolactinaemia: successful treatment but adverse consequences.

It is accepted that care must be taken in initiating testosterone replacement in hypogonadal individuals with historically low androgen levels. However less is reported about the influence of restoration of normal endogenous testosterone production on behaviour.Here we report how the adverse sequelae of successful treatment of hypogonadism secondary to hyperprolactinaemia, manifesting as irritability and low threshold to aggression, were managed through a joint approach between psychiatrist and physician.

Screening for hypogonadism in diabetes 2008/9: results from the Cheshire Primary Care cohort.

Aim: There is increasing awareness of hypogonadism in men with type 2 diabetes but limited data from Primary Care.

Subjects And Methods: The anonymised records of 6457 male patients aged 18-80 years with diabetes were accessed. Within the last 2 years 391 men (6.