Publications by authors named "S Bujan"
Article Synopsis
- The study aimed to assess microcirculation abnormalities in patients with Behçet's Syndrome (BS) and their link to vascular issues using nailfold videocapillaroscopy (NVC).
- Out of 65 patients, 36.9% showed vascular involvement, with NVC revealing abnormalities like tortuous capillaries and microhaemorrhages in nearly half of the participants.
- Significant correlations were found between specific NVC abnormalities and vascular complications, indicating that NVC could be useful for early identification of patients at risk for vascular events.
Breast cancer is currently one of the most prevalent cancers worldwide. The mechanisms by which pesticides can increase breast cancer risk are multiple and complex. We have previously observed that two aryl hydrocarbon receptor (AhR) agonists ‒pesticides hexachlorobenzene (HCB) and chlorpyrifos (CPF)‒ act on tumor progression, stimulating cell migration and invasion in vitro and tumor growth in animal models.
View Article and Find Full Text PDFThe hydrodynamics of karst terrain are highly complex due to the diverse fractures and reservoirs within limestone formations. The time delay between rainfall events and subsequent flow into reservoirs exhibits significant variability. However, these hydrological processes are not easily visualized in karst topography.
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- VEXAS syndrome is an adult-onset autoinflammatory disease caused by postzygotic genetic variants, affecting males with symptoms like skin lesions, fever, and arthritis at a mean age of 67.5 years.
- In a study of 42 patients, 30 were identified with pathogenic genetic variants and showed varying degrees of glucocorticoid dependence for symptom management.
- The research revealed that these variants were present in both blood and non-blood tissues, challenging the previous understanding that these genetic changes were limited to myeloid (blood) cells.
Breast cancer is the most common invasive malignancy among women worldwide and constitutes a complex and heterogeneous disease. Interest has recently grown in the role of the aryl hydrocarbon receptor (AhR) in breast cancer and the contribution of environment-polluting AhR agonists. Here, we present a literature review addressing AhR ligands, including pesticides hexachlorobenzene and chlorpyrifos, polycyclic aromatic hydrocarbons, polychlorinated dibenzo-p-dioxins and dibenzofurans, polychlorinated biphenyls, parabens, and phthalates.
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