Publications by authors named "S Brule"

Introduction: In Canada, those who are or who could become pregnant are recommended to consume a daily multivitamin containing 400 μg of folic acid to help prevent neural tube defects.

Objectives: To report the prevalence and determinants of folic acid-containing supplement use among females of childbearing age in Canada.

Methods: Data were combined from cycles 2015/16 and 2017/18 of the maternal experiences module of the cross-sectional Canadian Community Health Survey, which was completed by females aged 15-55 years.

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Cancer patients receiving non-endocrine therapies are at risk of hepatitis B virus (HBV) reactivation (HBVr). Guidelines recommend HBV screening prior to treatment. The Ottawa Hospital Cancer Center implemented a screening pilot for all patients receiving FOLFOX-based regimens between January and April 2023.

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Article Synopsis
  • The study highlights the significance of introducing iron-rich solid foods in a breastfed infant's diet, revealing that 65.8% of Canadian mothers adhered to this guideline at around 6 months of age.
  • Infant cereal was the most common first solid food introduced (66.1%), with rural mothers showing higher adherence.
  • Factors affecting adherence included lower odds among mothers from the Western provinces and specific racial and social demographics, indicating a need for increased education and support for diverse populations.
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Article Synopsis
  • - The inhalation of respirable crystalline silica, particularly quartz, is linked to serious health issues like lung inflammation, fibrosis, cancer, and autoimmune diseases, with nearly free silanols (NFS) from fractured quartz being key players in this toxicity.
  • - Experiments on mice showed that exposure to NFS-rich quartz caused significant acute and long-term inflammatory responses, fibrosis, cancer, and autoimmune signs, while NFS-poor quartz showed no such effects.
  • - The study highlights that NFS-rich quartz specifically triggers harmful biological responses, including increased pro-inflammatory cytokines, lung fibrosis markers, tumors, and autoantibodies, underscoring its health risks compared to less reactive quartz forms.
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Objective: To assess the association between work location and movement behaviours (physical activity [PA], screen time, sleep) and adherence to the Canadian 24-Hour Movement Guidelines (24-H Guidelines) among Canadian workers during the COVID-19 pandemic.

Methods: Using cross-sectional data from the 2021 Canadian Community Health Survey (n = 10,913 working adults 18-75 years), primary work location was categorized as: worked outside the home at a fixed location (fixed workplace), worked at home (telework), and worked outside the home at no fixed location (non-fixed workplace). Recreational, transportation and occupational/household PA, as well as leisure screen time and sleep duration were self-reported.

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